What is the best time to take medicines for hypertension, in the morning or in the evening?

At bedtime, to curb the early morning blood pressure surge on awakening that correlates with a higher incidence of heart attacks and strokes around 8 – 12 am. Taking long acting calcium channel blickers e.g. amlodipine and/or longacting diuretics e.g. chlorthalidone is helpful too.

Early morning blood pressure surge can be avoided by dosing carvedilol in the evening see http://www.med.or.jp/english/pdf/2005_08/398_403.pdf

From Morning Surge in Blood Pressure and Cardiovascular Risk

From The Morning Risk Zone

Higher incidence of heart attacks early morning see Circadian Variation – Increased Morning Incidence of Acute Myocardial Infarction in Patients with Coronary Artery Disease

The best time is when your doctor or pharmacist told you you should take them, not what random people on the internet recommend.

If your doctor or pharmacist didn’t tell you or if you forgot, ask them.

I know this is a really generic answer, but these sorts of questions really are best answered by medical professionals who know what they’re doing, know your medical history and know why they’re prescribing this specific medicine.

It really depends on which medicines you are taking. Through experience, we recommend that beta blockers are best taken in the morning as they can cause sleep disturbances in the night as a side effect. Diuretics are also better taken in the morning as you don’t want to make multiple trips to the bathroom at night. Other meds like amlodipine can be taken at night to help control the early morning rise in BP.

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